BP305P. PHARMACEUTICAL ORGANIC CHEMISTRY -II (Practical)

B. Pharm. 2nd Year (3rd Semester)

I Experiments involving laboratory techniques  Recrystallization
 Steam distillation
II Determination of following oil values (including standardization of
reagents)  Acid value  Saponification value  Iodine value
III Preparation of compounds  Benzanilide/Phenyl benzoate/Acetanilide from Aniline/ Phenol
/Aniline by acylation reaction.  2,4,6-Tribromo aniline/Para bromo acetanilide from Aniline/  Acetanilide by halogenation (Bromination) reaction.  5-Nitro salicylic acid/Meta di nitro benzene from Salicylic acid /
Nitro benzene by nitration reaction.  Benzoic acid from Benzyl chloride by oxidation reaction.  Benzoic acid/ Salicylic acid from alkyl benzoate/ alkyl salicylate by
hydrolysis reaction.  1-Phenyl azo-2-napthol from Aniline by diazotization and coupling
reactions.  Benzil from Benzoin by oxidation reaction.  Dibenzal acetone from Benzaldehyde by Claison Schmidt reaction
 Cinnammic acid from Benzaldehyde by Perkin reaction
 P-Iodo benzoic acid from P-amino benzoic acid